Throw physic to the dogs; I'll none of it

Throw physic to the dogs; I'll none of it

The line "Throw physic to the dogs; I'll none of it" is spoken by Macbeth in Act 5, Scene 3 of William Shakespeare's play Macbeth. In this scene, Macbeth is facing the final battle against Malcolm's forces, and he is feeling the weight of his guilt and the consequences of his actions. The line reflects Macbeth's growing despair and his realization that no amount of medicine or healing can cure the sickness in his soul.